The traditional central dogma in cell biology is regarded as gene-mRNA-protein.That is，transfers from DNA to mRNA and syntheses of a wide variety of structural and functional proteins，which contribute to maintain the cell form and to keep cell function，respectively.Genes corresponding to synthesis of certain protein are usually several or even dozens.How does the cell maintain its activity and life in the existence of thousands or even more than ten thousand proteins？How do these proteins play their role cross-talking and interacting with each others？However，these subjects are not completely clarified even by the up-date genome protein researches.Proteins are essential for the cell activity and function，and protein interaction is the key of cell behaviors.Therefore，researches and knowledge on proteomics become important unavoidably.